6-maleimidohexanoic acid pentafluorophenyl ester

6-maleimidohexanoic acid pentafluorophenyl ester - Names and Identifiers

Name	6-maleimidohexanoic acid pentafluorophenyl ester
Synonyms	6-Maleimidocaproic acid-PFP ester 6-maleimidohexanoic acid pentafluorophenyl ester Perfluorophenyl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, pentafluorophenylester 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,3,4,5,6-pentafluorophenyl ester
CAS	692739-25-6

6-maleimidohexanoic acid pentafluorophenyl ester - Physico-chemical Properties

Molecular Formula	C16H12F5NO4
Molar Mass	377.262796

6-maleimidohexanoic acid pentafluorophenyl ester - Upstream Downstream Industry

Downstream Products

MC-Val-Cit-PAB

6-maleimidohexanoic acid pentafluorophenyl ester - Introduction

6-maleimidohexanoic acid pentafluorophenyl ester (6-maleimidohexanoic acid pentafluorophenyl ester) is an organic compound with the chemical formula C17H11F5NO3.

Nature:
-Appearance is white solid.

Use:
- 6-maleimidohexanoic acid pentafluophenyl ester is mainly used as a chemical cross-linking agent and can be used in the fields of biomarkers, protein modification and drug synthesis.
-The compound can selectively react with biological macromolecules (such as proteins or polypeptides) containing sulfhydryl groups to form stable covalent bonds, which can be used to construct biological materials and prepare antibody coupling reagents.

Method:
-The preparation of 6-maleimidohexanoic acid pentafluorophenyl ester is usually completed by a two-step reaction.
-First, maleic anhydride is reacted with adipic anhydride to synthesize maleimidohexanoic acid.
-Then, maleimidocaproic acid is reacted with pentafluorophenyl tetrafluoroborate to form an ester structure under alkaline conditions.

Safety Information:
- 6-maleimidohexanoic acid pentafluophenyl ester should be used and stored to prevent contact with skin, eyes and respiratory tract.
-Wear protective gloves, goggles and respiratory protection when used.
-Operate under suitable ventilation conditions and store in sealed condition.
-Keep it well and away from ignition and oxidizing agents.
-Before use should consult the relevant safety technical instructions.

Last Update：2024-04-09 21:01:54